Bremelanotide, marketed under the name Vyleesi®, is a synthetic peptide analog of the naturally occurring melanocortin hormone. It works by activating melanocortin receptors in the brain, influencing pathways associated with sexual desire, mood, and neuroendocrine regulation.
Bremelanotide (Vyleesi®) is FDA-approved for premenopausal women with acquired, generalized hypoactive sexual desire disorder (HSDD). Researchers and clinicians are also studying its broader physiological effects on melanocortin pathways, which are involved in sexual function, appetite regulation, and stress response.
At Alpha Hormones® in Pasadena, California, our licensed medical team provides educational consultations to help patients understand the science, safety, and responsible use of peptide-based options such as Bremelanotide.
Bremelanotide has become an area of growing interest in sexual wellness and neuroendocrine medicine. Through its effects on the melanocortin system, it helps modulate signals that influence libido and mood.
Clinical and research areas include:
While FDA approval currently applies only to women with HSDD, emerging clinical discussions explore how men may also benefit from modulation of melanocortin pathways under professional supervision. Such uses are considered off-label and always require an individualized medical assessment.
At Alpha Hormones®, we offer personalized consultations to determine whether peptide therapy aligns with your wellness goals. Our providers review FDA-approved indications, discuss off-label considerations when appropriate, and emphasize safe, medically guided care.
Available delivery methods include:
What to expect:
Some individuals report transient effects within hours, while others experience more gradual changes. Commonly reported temporary side effects include mild nausea, flushing, or headache. All potential reactions are reviewed prior to administration.
Our Bremelanotide formulations are sourced only from GMP-compliant, licensed pharmacies, ensuring consistency and safety.
Individuals who explore Bremelanotide therapy at Alpha Hormones® are often those who:
Every patient begins with a private consultation to review health history, hormones, and goals. Our providers create an individualized plan focused on safety, education, and empowerment.
Yes — Bremelanotide (Vyleesi®) is FDA-approved for the treatment of hypoactive sexual desire disorder (HSDD) in premenopausal women. All other uses, including in men, are considered off-label and must be discussed with a licensed medical provider.
It is a melanocortin receptor agonist, meaning it influences neural pathways related to sexual desire and arousal, rather than acting on hormones directly.
Typically as a subcutaneous injection before anticipated intimacy. Some compounding pharmacies may also prepare intranasal or oral formulations for research or wellness contexts.
Some individuals report noticeable changes within hours, but experiences vary. Bremelanotide should be used only under professional guidance.
The most common side effects include temporary nausea, flushing, and mild headache. Most are short-lived and dose-related.
While not FDA-approved for men, Bremelanotide’s mechanism of action is not sex-specific. Some clinicians discuss off-label use for men in select cases, always with informed consent and medical oversight.
At Alpha Hormones® in Pasadena, we specialize in hormone and peptide-based wellness designed around individualized care and transparency.
✨ Interested in learning more about Bremelanotide (Vyleesi®)?
Schedule a confidential consultation with one of our licensed medical providers to discuss whether this therapy may be appropriate for you.
Bremelanotide (Vyleesi®) is FDA-approved only for premenopausal women with HSDD. Any other uses discussed are considered off-label. This page is for educational purposes only and does not constitute medical advice. Results vary, and no outcomes are guaranteed.
Alpha Hormones® complies with FTC and FDA communication guidelines. No unsubstantiated claims of efficacy are made. Patient experiences are individual and not indicative of typical results. All treatment decisions should be made in consultation with a licensed clinician.